Mauro Carcelli
Curriculm Vitae
Mauro Carcelli was born in 1965 and graduated in chemistry at Parma in 1990 (110/110 cum laude). He is Associate Professor of General and Inorganic Chemistry (CHIM03) in Parma since 1.10.2003.
He is co-author of 74 articles and 4 chapters on books (H-factor = 23).
Main field of scientific activity: Synthesis and spectroscopic characterization of coordination and organometallic compounds for: 1) bio-inorganic application; 2) coordination/activation of small molecules.
Grants
Principal investigator. Progetto Giovani Ricercatori e Ricercatori Singoli dell’Università di Parma “Nuovi derivati della fenantrolina nella complessazione dei lantanidi” (esercizio finanziario 2000).
Core Patner nell’ambito del progetto quadriennale (1998-2001) PRA CADY Cell cALcium DYnamics. Development of integrated methods for imaging and controlling intracellular calcium in living cells, Istituto Nazionale Fisica della Materia, Project Manager prof. Giorgio Rispoli.
Local unit member. COFIN 2004, Aspetti molecolari di patologie conformazionali proteiche. Ruolo dei fattori ambientali sulle variazioni strutturali di proteine per la progettazione e la sintesi di agenti ad attività antiaggregante, antiossidante, antiglicante e chelante nonché per applicazioni in diagnostica, coordinatore nazionale prof. Enrico Rizzarelli.
Local unit member. Progetti di ricerca fondamentale o di base, legge regionale 7 agosto 2007, n.7 : “Promozione della ricerca scientifica e dell’innovazione tecnologica in Sardegna”, Sviluppo di nanodevices innovativi ad azione sito-specifica per la prevenzione, diagnosi e terapia del carcinoma prostatico, coordinatore scientifico dott. Mario Sechi, anno finanziario 2010.
Local unit member. PRIN 2012, A multi-targeted molecular approach to block HIV-1 replication, coordinatore nazionale prof. Maurizio Botta (in corso)
List of the 5 most significant publications
- Mauro Carcelli, Dominga Rogolino, Alessia Bacchi, Gabriele Rispoli, Emilia Fisicaro, Carlotta Compari, Mario Sechi, Annelies Stevaert, Lieve Naesens, Metal-Chelating 2-Hydroxyphenyl Amide Pharmacophore for Inhibition of Influenza Virus Endonuclease, Molecular Pharmaceutics, 2014, 11, 304−316.
- Mario Sechi, Alessio Innocenti, Nicolino Pala, Dominga Rogolino, Mauro Carcelli, Andrea Scozzafava, Claudiu T. Supuran, Inhibition of a-class cytosolic human carbonic anhydrases I, II, IX and XII, and b-class fungal enzymes by carboxylic acids and their derivatives: New isoform-I selective nanomolar inhibitors, Bioorg. Med. Chem. Lett., 2012, 22, 5801–5806.
- Dominga Rogolino, Mauro Carcelli, Mario Sechi, Nouri Neamati, Viral enzymes containing magnesium: metal binding as a successful strategy in drug design, Coord. Chem. Rev., 2012, 256, 3063-3086.
- Alessia Bacchi, Mauro Carcelli, Fabrizio Carta, Emilia Fisicaro, Dominga Rogolino, Mario Sechi, Martin Sippel, Christoph Sotriffer, Tino W. Sanchez, Nouri Neamati, From Ligand to Complexes. Part 2. Remarks on Human Immunodeficiency Virus Type 1 Integrase inhibition by β-Diketo Acid Metal Complexes, Journal of Medicinal Chemistry, 51, 7253–7264, 2008.
- Bacchi, M. Carcelli, P. Pelagatti, G. Pelizzi, M.C. Rodriguez-Arguelles, D. Rogolino, C. Solinas, F. Zani, Antimicrobial and mutagenic properties of organotin(iv) complexes with isatin and n-alkylisatin bisthiocarbonohydrazones, Journal of Inorganic Biochemistry, 2005, 99/2, 397-408.